Mixing Alcohol and Ativan (Lorazepam)?

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Mixing Ativan (Lorazepam) and alcohol is a topic that demands careful attention and understanding, particularly within the context of addiction and recovery. Ativan, a prescription medication commonly used to manage anxiety disorders, and alcohol, a widely consumed substance in social settings, can have potentially dangerous combined interactions. Recognizing the risks involved in this combination and its potential consequences on individuals’ physical and mental well-being is crucial.

Ativan belongs to a class of drugs known as benzodiazepines, which work by enhancing the effects of gamma-aminobutyric acid (GABA), a neurotransmitter that slows down brain activity. This results in a calming effect and can help individuals manage anxiety symptoms. On the other hand, alcohol is a central nervous system depressant that affects multiple neurotransmitters, leading to various effects, such as relaxation, euphoria, and impaired coordination.

When Ativan and alcohol are mixed, their effects on the central nervous system can be amplified and potentially hazardous. Both substances act as depressants, which means their combined use can result in increased sedation, respiratory depression, and impaired cognitive function. Furthermore, the interaction between Ativan and alcohol can exacerbate the risk of accidents, falls, and other dangerous situations, particularly when driving or operating machinery.

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Can You Mix Alcohol & Ativan (Lorazepam)?

Mixing alcohol and Ativan (Lorazepam) is not recommended due to the potential risks and dangers. Both substances are central nervous system (CNS) depressants, meaning they sedate the brain and can slow down vital functions. When combined, alcohol and Ativan can have an additive effect, intensifying the depressant properties and leading to serious consequences.

One of the primary concerns with mixing alcohol and Ativan is the increased risk of respiratory depression. Both substances can suppress breathing, and when used together, they can significantly impair respiratory function, leading to shallow or labored breathing. This can be particularly dangerous, especially for individuals with underlying respiratory conditions or those who consume high amounts of alcohol or Ativan.

Furthermore, combining alcohol and Ativan can lead to heightened sedation and impaired cognitive function. This can result in decreased coordination, difficulty concentrating, and impaired judgment, increasing the risk of accidents, falls, and other dangerous situations. It’s important to note that these effects can vary depending on the individual’s tolerance, dosage, and other factors, but the potential for adverse outcomes remains.

What Is Ativan & What Does It Treat?

Ativan is a prescription medication classified as a benzodiazepine. It is primarily used to treat anxiety disorders and relieves symptoms such as excessive worry, restlessness, and tension. Ativan is also prescribed for the short-term management of anxiety associated with other conditions like insomnia, panic attacks, and certain medical procedures.

As a benzodiazepine, Ativan enhances the effects of gamma-aminobutyric acid (GABA), a neurotransmitter in the brain that helps regulate neuronal excitability. Increasing GABA activity reduces excessive brain activity and promotes relaxation. This mechanism of action makes it effective in alleviating anxiety symptoms and inducing sedation.

In addition to its use in anxiety disorders,  Ativan may be prescribed as an adjunctive medication in treating other conditions, such as seizures, and for managing alcohol withdrawal symptoms. However, it is important to note that Ativan is intended for short-term use due to the potential for dependence and the risk of developing a tolerance over time.

Known Symptoms & Side Effects of Lorazepam Use

Lorazepam is a medication that can provide therapeutic benefits for individuals with anxiety disorders or other conditions requiring short-term treatment. However, like any medication, it can also cause side effects. It is essential to be aware of these potential side effects, which vary in frequency and severity among individuals.

  • Common Side Effects – Common side effects are typically mild, subsiding as the body adjusts to the medication. They may include drowsiness, dizziness, weakness, fatigue, blurred vision, and a feeling of sedation.
  • Cognitive and Motor Impairment – Lorazepam can cause impaired cognitive function, including difficulties with concentration, memory, and coordination. These effects can interfere with daily activities, such as driving or operating machinery. It is crucial to avoid engaging in tasks that require alertness until you know how the medication affects you personally.
  • Paradoxical Reactions – In some cases, lorazepam can have paradoxical effects, meaning it may cause agitation, restlessness, irritability, increased anxiety, or other changes in behavior. If you experience these reactions, it is important to contact your healthcare provider.
  • Respiratory Depression – Lorazepam, like other benzodiazepines, can depress the respiratory system at high doses or when combined with other CNS depressants, such as alcohol or opioids. This can result in slowed or shallow breathing, which can be dangerous. It is crucial to use lorazepam as prescribed and avoid combining it with other substances without medical supervision.
  • Withdrawal and Dependence – Long-term or high-dose use of lorazepam can lead to physical dependence, and sudden discontinuation can cause withdrawal symptoms such as rebound anxiety, insomnia, irritability, muscle aches, and tremors. It is important to follow your healthcare provider’s instructions for gradually tapering off the medication if it is no longer needed.

Can You Take Ativan If You Have Been Drinking?

Combining Ativan with alcohol is not recommended due to its potential risks and dangers. Ativan and alcohol are central nervous system (CNS) depressants, meaning they have a soothing effect on the brain and can slow down vital functions. Taking Ativan after consuming alcohol can intensify the depressant effects and lead to increased sedation, impaired cognitive function, and respiratory depression.

Alcohol itself can impair judgment, coordination, and cognitive abilities. Adding Ativan can amplify these effects and increase the risk of accidents, falls, and other dangerous situations. Combining Ativan and alcohol can also lead to memory loss, increased sedation, and prolonged impairment.

Moreover, alcohol can interfere with the metabolism and elimination of medications, potentially altering how the body processes Ativan. This can lead to unpredictable and potentially harmful effects, including an increased likelihood of experiencing side effects or adverse reactions from Ativan.

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How Does Ativan Interact With Alcohol in the Body?

The interaction between Ativan and alcohol in the body involves complex pharmacological effects. Both substances are central nervous system (CNS) depressants, meaning they can slow down brain activity and have sedative effects. When Ativan and alcohol are taken together, their effects can be additive and potentially dangerous. Here’s a breakdown of how Ativan interacts with alcohol in the body:

  • Enhanced Sedation – Ativan and alcohol both have sedative properties and when combined, they can intensify sedation. This can result in increased drowsiness, difficulty staying awake, and a higher risk of falling asleep inappropriately. It is crucial to avoid activities that require alertness, such as driving or operating machinery when using Ativan and alcohol together.
  • Increased Respiratory Depression –  Ativan and alcohol can suppress the respiratory system, reducing the rate and depth of breathing. Together, their combined effect can further depress respiration, potentially leading to shallow or slowed breathing. This is a significant concern as it can result in oxygen deprivation and respiratory failure, especially at higher doses or in individuals with pre-existing respiratory conditions.
  • Impaired Cognitive Function – Ativan and alcohol can impair cognitive function individually, affecting memory, judgment, coordination, and reaction time. Combining the two substances can exacerbate these impairments, leading to significant cognitive deficits. This can result in confusion, difficulty concentrating, and impaired decision-making abilities.

Increased Risk of Overdose – Mixing Ativan and alcohol also raises the risk of overdose. Both substances act on the GABA receptors in the brain, and their combined effects can lead to a more pronounced inhibition of neuronal activity. This can result in excessive sedation, loss of consciousness, and a potentially life-threatening overdose.

Can You Consume Alcohol While Taking Anxiety Medication?

It is generally advised to avoid consuming alcohol while taking anxiety medication, such as Ativan (Lorazepam). Combining alcohol and anxiety medication can have various negative effects:

  • Increased Sedation and Impairment – Both alcohol and anxiety medications have sedative effects on the central nervous system. Taking them together can intensify sedation, leading to excessive drowsiness, reduced alertness, and impaired cognitive function. This poses risks, especially when engaging in activities that require focus and coordination.
  • Reduced Effectiveness of Medication – Alcohol can interfere with the way anxiety medications work in the body. It may impact their metabolism, potentially reducing their desired effects. This can result in inadequate symptom relief and decreased benefits from the medication.
  • Potential for Adverse Side Effects – Combining alcohol and anxiety medication can increase the likelihood of experiencing adverse side effects. These may include dizziness, confusion, breathing difficulties, changes in blood pressure, and increased heart rate. Some combinations of alcohol and specific anxiety medications can even lead to severe side effects and life-threatening complications.

Increased Risk of Dependence and Addiction – Both alcohol and anxiety medications have the potential for dependence and addiction. Using them together can heighten the risk of developing these issues. It is important to follow your healthcare provider’s instructions regarding anxiety medication usage and to avoid alcohol consumption to reduce the chances of substance misuse or addiction.

Can Consuming Alcohol Worsen Anxiety Symptoms?

Consuming alcohol can worsen anxiety symptoms for many people. While alcohol initially may temporarily relieve anxiety, its effects can ultimately lead to increased anxiety and exacerbation of anxiety disorders. Here’s why alcohol can worsen anxiety symptoms:

  • Disruption of Neurotransmitters – Alcohol affects brain neurotransmitters such as GABA and serotonin, which regulate mood and anxiety. While alcohol initially increases GABA activity, leading to relaxation, it can disrupt neurotransmitter balance over time. This can result in rebound anxiety as GABA levels decrease.
  • Increased Anxiety Sensitivity – Alcohol can heighten anxiety sensitivity, making individuals more prone to experiencing anxiety symptoms even in non-anxiety-provoking situations. This can lead to heightened unease and restlessness.
  • Impact on Sleep Quality – Alcohol disrupts sleep patterns, reducing deep restorative and REM sleep. Poor sleep can increase anxiety symptoms, restlessness, and irritability during waking hours.
  • Negative Effects on Mood and Mental Health – Alcohol is a depressant and can worsen symptoms of depression and other mood disorders that often coexist with anxiety disorders. Worsening mood symptoms can intensify anxiety symptoms as well.
  • Interference with Anxiety Medication – Alcohol can interfere with the effectiveness of anxiety medication, potentially reducing its benefits and worsening anxiety symptoms.

Can Alcohol Reduce the Effectiveness of Anxiety Medication?

Yes, alcohol consumption can reduce the effectiveness of anxiety medication. When alcohol and anxiety medication are combined, the interaction can interfere with the medication’s intended therapeutic benefits. This can result in reduced relief from anxiety symptoms and potentially diminish the desired effects of the medication. Therefore, it is generally recommended to avoid alcohol while taking anxiety medication to ensure optimal treatment outcomes.

Are There Dangerous Side Effects to Consuming Alcohol While on Ativan?

Combining alcohol and Ativan (Lorazepam) can have dangerous side effects and health risks. The simultaneous use of these substances can result in excessive sedation, impaired coordination, slowed breathing, and cognitive and motor impairment. There is an increased risk of accidents, falls, and respiratory failure. Mixing alcohol and Ativan can also lead to overdose and worsen mental health symptoms. To ensure your safety, it is strongly advised to avoid consuming alcohol while taking Ativan or any other benzodiazepine medication. Always follow the guidance of your healthcare provider and discuss any concerns you may have regarding the combination of alcohol and Ativan.

How Long Should You Wait After Taking Ativan to Consume Alcohol?

It is generally recommended to wait at least 24 hours after taking Ativan (Lorazepam) before consuming alcohol. Ativan is a long-acting benzodiazepine medication that can remain in your system for several hours after ingestion. Waiting for 24 hours helps ensure that the effects of Ativan have diminished and the drug has been mostly eliminated from your body.

However, it’s important to note that the timing may vary depending on individual metabolism, dosage, and overall health. It is always best to consult your healthcare provider for personalized advice regarding the appropriate waiting period before consuming alcohol after taking Ativan. They can provide guidance based on your specific circumstances and help ensure your safety and well-being.

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Ryan Soave


Ryan Soave brings deep experience as a Licensed Mental Health Counselor, certified trauma therapist, program developer, and research consultant for Huberman Lab at Stanford University Department of Neurobiology. Post-graduation from Wake Forest University, Ryan quickly discovered his acumen for the business world. After almost a decade of successful entrepreneurship and world traveling, he encountered a wave of personal and spiritual challenges; he felt a calling for something more. Ryan returned to school and completed his Master’s Degree in Mental Health Counseling. When he started working with those suffering from addiction and PTSD, he found his passion. He has never looked back.

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Cayla Clark

Cayla Clark grew up in Santa Barbara, CA and graduated from UCLA with a degree in playwriting. Since then she has been writing on addiction recovery and psychology full-time, and has found a home as part of the Guardian Recovery team.

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