Oxycodone Addiction Detox, Treatment, Rehab, and Long-Term Recovery

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Oxycodone addiction is a potentially life-threatening chronic brain disease that is notoriously challenging to overcome. Many people dependent on oxycodone and other opioids find that long-term treatment in a rehab facility is essential for sustaining lasting recovery. At Guardian Recovery Network, we offer comprehensive programs, individualized care plans, and a variety of therapeutic services and activities. Contact us today to learn more about our dedication to our clients to provide them with the tools, support, and resources they need to end active addiction and pursue the healthy, substance-free life they deserve.

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What Is the Addiction Treatment & Recovery Process for Oxycodone Addiction?

The addiction treatment and recovery process for oxycodone addiction typically involves several steps, including assessment, medical detox, inpatient rehab, outpatient programs, therapeutic treatment, and ongoing support from professionals and peers.

Detoxing From Oxycodone Use

Oxycodone medical detox is an around-the-clock process of discontinuing use while managing withdrawal symptoms and cravings using medication such as Suboxone. Critically, detoxing from oxycodone at home instead of in a clinical environment can result in potentially dangerous complications, such as dehydration and electrolyte imbalances. Withdrawal symptoms during oxycodone detox typically begin a few hours after the last dose.

The acute phase of withdrawal symptoms usually peaks within the first 24-72 hours after the last dose and includes both emotional and physical symptoms such as anxiety, insomnia, drug cravings, sweating, vomiting, stomach cramps, aches and pains, and more. Post-acute withdrawal (PAWS) symptoms, which can persist for several weeks after the acute phase has ended, mainly consist of psychological symptoms such as depression, anxiety, irritability fatigue, poor concentration, insomnia, and others.

Oxycodone Withdrawal Effects Timeline:

Days 1-2—Onset 12-24 hours after the last dose and can include restlessness, anxiety, agitation, sweating, insomnia, and muscle aches.

Days 3-5—Withdrawal symptoms peak, and can also include nausea, vomiting, diarrhea, stomach cramps, dilated pupils, chills, and an elevated heart rate.

Days 6-7—Withdrawal symptoms begin to improve during this time, but emotional symptoms can linger, such as depression, anxiety, and drug cravings.

Medication-Assisted Treatment Medications for Oxycodone Detox

Medication-assisted treatment (MAT) is a type of addiction treatment that involves the use of medications to manage withdrawal symptoms and cravings during the detox process. MAT should always be administered under the supervision of a qualified healthcare professional.

Medications Commonly Used in MAT for Oxycodone Include:

Methadone—A synthetic opioid that works by binding to the same receptors as oxycodone, but is longer-acting, therefore producing a more gradual effect. (1) This allows it to mitigate withdrawal symptoms and drug cravings that result from addiction.
Suboxone—A combination medication that contains buprenorphine, a partial opioid agonist, meaning it binds to the same receptors as oxycodone, but induces a weaker effect without euphoria. (2) Suboxone also contains naloxone, which can prevent an overdose if the drug is used excessively or tampered with. (3)

Naltrexone—An opioid antagonist that blocks the effects of other opioids in the brain. (4) It is typically used after completion of the acute withdrawal phase to help reduce cravings and prevent relapse.

How Long Are Addiction Treatment Programs?

After detox, available treatment programs typically range from 28 days to 90 days or longer, depending on the individual’s needs and the severity of their addiction. After completing inpatient or residential treatment, individuals can transition to outpatient treatment. This may last several months to a year or longer, depending on the person’s needs and how much they’ve progressed in their recovery.

Co-Occurring Disorders That May Exist Alongside Oxycodone Addiction

It’s not uncommon for individuals with oxycodone addiction to also have co-occurring mental health or medical disorders, which can complicate the treatment process and make recovery more challenging. Some common co-occurring disorders that may exist alongside oxycodone addiction include chronic pain, depression, anxiety, PTSD, and personality disorders.

Dual diagnosis treatment addresses co-existing disorders, typically involving a team of healthcare professionals who collaborate to provide integrated care. This can include medication, therapy, counseling, and support groups intended to address both conditions.

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What Are the Medical Treatment Options for Oxycodone & Opioid Addiction?

Treatment options for oxycodone dependence and addiction include inpatient rehab, partial hospitalization, outpatient and intensive outpatient programs.

Inpatient Rehab

Inpatient (residential) rehab involves living in a treatment facility around-the-clock while receiving intensive and comprehensive care for drug or alcohol addiction. Here, clients participate in individual and group therapy sessions, counseling, psychoeducation, and alternative therapies. (5) Inpatient rehab provides a safe environment free from triggers and temptations that may contribute to relapse. This format may be recommended for individuals with severe addiction, co-occurring mental health disorders, or a lack of support at home.

Partial Hospitalization Programs

partial hospitalization program (PHP) is a type of intensive outpatient program that provides structured and comprehensive treatment for individuals with substance abuse issues. PHPs offer a high level of support, and typically involve several hours of treatment per day, several days per week. However, the individual does not stay overnight at the facility and instead returns home at the end of the day.

Outpatient (OP) & Intensive Outpatient Programs (IOP)

Outpatient and intensive outpatient programs IOP require participation in treatment sessions multiple days per week, and do not include overnight stays at the facility. (6) IOP and OP include similar therapies, services, and activities featured in higher levels of care. They are designed to provide individuals with the support and resources they need to maintain their recovery outside of a structured treatment environment. IOP provides a higher level of care and support than OP, the main difference being the number of hours and days per week participation is required. The programs are often recommended for those with less severe disorders and who have a solid support system.

Virtual & Online Treatment & Counseling

Virtual and internet-based treatment and counseling for addiction refer to addiction treatment services that are delivered through the internet or other forms of digital communication. It can include a range of services, such as teletherapy, online support groups, counseling, and educational resources. The benefits of virtual and online addiction treatment include increased accessibility and convenience.

Behavioral Treatment Methods & Therapies Used in Oxycodone Addiction Treatment

A variety of behavioral treatment and therapy methods are used to treat oxycodone, including cognitive and dialectical behavioral therapies, motivational interviewing, and individual, group, and family therapy.

Cognitive Behavioral Therapy (CBT)

Cognitive Behavioral Therapy (CBT) is based on the idea that thoughts, feelings, and behaviors are all interrelated, and these can contribute to mental health conditions and other issues. CBT involves working with a therapist to identify and challenge negative thought patterns and beliefs that may be contributing to addiction and other psychiatric issues.

Dialectical Behavioral Therapy (DBT)

Dialectical Behavioral Therapy (DBT) is based on the idea that some individuals struggle with regulating their emotions and have difficulty dealing with stress and intense feelings. The goal of this therapy is to help them develop skills to manage their emotions, improve their relationships, and cope with stress in a healthy way.

Motivational Interviewing

Motivational interviewing (MI) is a non-judgmental counseling approach that aims to help individuals resolve their ambivalence or resistance to enacting life changes. During MI sessions, the therapist works collaboratively with the individual to explore and overcome obstacles (such as a lack of motivation) preventing them from changing.

Individual Therapy

Individual therapy is designed to help individuals overcome addiction by exploring and addressing the underlying issues that contribute to addictive behavior. This therapy is typically led by a licensed therapist or counselor who specializes in addiction treatment. During individual therapy sessions, individuals work with their therapist to identify triggers for substance use and develop coping skills to manage cravings and withdrawal symptoms.

Group Therapy

Group therapy for addiction involves a group of people struggling with addiction collaborating with a licensed therapist or counselor. It’s designed to provide individuals with a supportive environment to share experiences, explore underlying issues, learn from others, and develop coping skills to manage their addiction.

Family Therapy

Family therapy involves the participation of family members in the addiction treatment process. The therapy is designed to help family members understand and address the impact addiction has on the family system. It is also designed to provide support for both the individual struggling with addiction and their loved ones.

Sober Living, Aftercare, & Long-Term Recovery

Sober living options and aftercare following formal addiction treatment are essential to help individuals maintain sobriety and prevent relapse over the long term. Sober living homes offer a supportive living environment for individuals in early recovery. Aftercare planning ensures that individuals have access to ongoing support and treatment, such as therapy and 12-step programs. To achieve long-term recovery, individuals must be provided with and make effective use of the tools they need to maintain sobriety and well-being indefinitely.

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Contact Guardian Recovery Network Today

Guardian Recovery Network offers a wide range of services and programs designed to help individuals overcome addiction and achieve long-term recovery. These include medical detox, inpatient and outpatient treatment, cognitive-behavioral therapy, medication-assisted treatment, peer support groups, and aftercare. We aim to address the physical, psychological, and emotional aspects of addiction to help individuals achieve and sustain long-lasting recovery.

For a free, no-obligation assessment and health insurance benefits check, contact us to speak with a Treatment Advisor and learn more about our streamlined admissions process and full continuum of care. We can help you begin your recovery journey and guide you every step of the way.


Do I have an Addiction issue?

Disclaimer: Does not guarantee specific treatment outcomes, as individual results may vary. Our services are not a substitute for professional medical advice or diagnosis; please consult a qualified healthcare provider for such matters.

  1. https://www.samhsa.gov/medications-substance-use-disorders/medications-counseling-related-conditions/methadone
  2. https://www.samhsa.gov/medications-substance-use-disorders/medications-counseling-related-conditions/buprenorphine
  3. https://www.narcan.com/
  4. https://www.samhsa.gov/medications-substance-use-disorders/medications-counseling-related-conditions/naltrexone
  5. https://www.sciencedirect.com/science/article/abs/pii/S0079612317301140
  6. https://online.regiscollege.edu/blog/inpatient-vs-outpatient/

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Reviewed professionally for accuracy by:

Ryan Soave


Ryan Soave brings deep experience as a Licensed Mental Health Counselor, certified trauma therapist, program developer, and research consultant for Huberman Lab at Stanford University Department of Neurobiology. Post-graduation from Wake Forest University, Ryan quickly discovered his acumen for the business world. After almost a decade of successful entrepreneurship and world traveling, he encountered a wave of personal and spiritual challenges; he felt a calling for something more. Ryan returned to school and completed his Master’s Degree in Mental Health Counseling. When he started working with those suffering from addiction and PTSD, he found his passion. He has never looked back.

Written by:

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Cayla Clark

Cayla Clark grew up in Santa Barbara, CA and graduated from UCLA with a degree in playwriting. Since then she has been writing on addiction recovery and psychology full-time, and has found a home as part of the Guardian Recovery team.

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